Principal Investigator
· Principal Investigator ·
Wanhua Shen
沈万华
Dr. Wanhua Shen is Principal Investigator at the College of Life and Environmental Sciences, Hangzhou Normal University. He trained at the Scripps Research Institute in Hollis Cline's lab, where he developed deep expertise in Xenopus in vivo electrophysiology and imaging. His research program centers on the molecular and cellular mechanisms governing neural circuit construction, excitation-inhibition balance, and experience-dependent plasticity, with implications for neurological disorders including autism and epilepsy.
Neural Circuits
Xenopus laevis
E/I Balance
Synaptic Plasticity
Epigenetics
Graduate Students & Researchers
Current Members
Han Lu
韩璐
Associate Professor
Neurotoxicity of environmental pollutants and neuroprotective mechanisms in Xenopus
Chen Qi
陈齐
Research Scientist
Excitation-inhibition balance and its role in neurodevelopmental disorders
Wu Xiaohua
吴晓华
Research Associate
Neural circuit plasticity and AMPA receptor trafficking in the developing visual system
Duan Xinyi
段馨怡
Graduate Student
Experience-dependent structural plasticity and dendritic morphogenesis by TrpM in vivo
Huang Wenyi
黄文毅
Graduate Student
Epigenetic regulation of visual experience-dependent synaptic homeostasis
Wu Yufei
吴钰飞
Graduate Student
Experience-dependent structural plasticity and dendritic morphogenesis by Flot in vivo
Lin Qihui
林琪慧
Graduate Student
Rab5c-mediated AMPAR endocytosis and synaptic downscaling mechanisms
Zhang Xingyue
张兴月
Graduate Student
β-Catenin/SOX2 signaling in neural stem cell fate decisions
Zhong Yuchen
钟雨晨
Graduate Student
Retinotectal circuit development and optomotor behavior
Ji Xueling
纪雪玲
Graduate Student
Single-cell transcriptomics of the developing Xenopus nervous system
Your position
Your position
Graduate Student
Ca²⁺ signaling and photocatalytic manipulation of neural activity
Your position
Your position
Graduate Student
Inhibitory synapse development and GABAergic circuit formation
Former Members
Lab Alumni
| Name | Degree | Research Focus | Current Position |
|---|---|---|---|
| Ruan Hangze (阮杭泽) | MS | HDAC1 and visual plasticity | Academic Research |
| Qi Xianjie (祁羡杰) | MS | Nascent proteins in synaptic plasticity | Industry |
| Gao Juanmei (高娟妹) | PhD | HDAC regulation and Xenopus neurotoxicology | Research Scientist |
| Zheng Lijun (郑丽君) | MS | AMPA receptor trafficking and synaptic plasticity | Research Scientist |
| Chen Peiyao (陈佩瑶) | MS | Radial glial cell proliferation; Single-cell atlas | Teacher |
| Lu Yufang (卢雨芳) | MS | LncRNA in neural development and plasticity | Teacher |