Peer-Reviewed Work

Publications

Publications spanning neural circuits, synaptic plasticity, epigenetics, and neurotoxicology. * corresponding author; # co-first author.

2003 – 2026
Home/Publications
20261 paper
1
Commun Biol ★ Latest
Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking
Zheng L, Duan X, Huang W, Luo Y, Wu Y, Lin Q, Wu X, Han L, Shen W.*
PubMed DOI
Commun Biol
20251 paper
2
Environ Pollut
Oxidative stress-mediated neurotoxicity of para-xylene and neuroprotection by gluconolactone in Xenopus laevis
Han L, Huang W, Meng L, Duan X, Wu Y, Lin Q, Wu X, Chen Q, Shen W.*
PubMed DOI
Environ Pollut
20241 paper
3
Sci Adv
Photocatalytic manipulation of Ca²⁺ signaling for regulating cellular and animal behaviors via MOF-enabled H₂O₂ generation
Zhang Z#, Luo Y#, Ma Y, Zhou Y, Zhu D*, Shen W.H.*, Liu J*
PubMed DOI
Sci Adv
20231 paper
4
Int J Mol Sci
β-Catenin and SOX2 Interaction Regulate Visual Experience-Dependent Cell Homeostasis in the Developing Xenopus Thalamus
Gao J, Lu Y, Luo Y, Duan X, Chen P, Zhang X, Wu X, Qiu M, Shen W.H.*
PubMed DOI
IJMS
20221 paper
5
Nat Commun ★ Single-cell Atlas
Cell landscape of larval and adult Xenopus laevis at single-cell resolution
Liao Y, Ma L, Guo Q, et al. Shen W.H.*, Guo G*, Han X*
PubMed DOI
Nat Commun
20213 papers
6
Front Cell Neurosci
Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II+ Oligodendrocytes and Myelin Fiber Size
Mei R, Huang L, Wu M et al. Shen W.H., Qiu M
PubMed DOI
Front Cell Neurosci
7
Cold Spring Harb Protoc
Electrophysiological Recording for Study of Xenopus Retinotectal Circuitry
Luo Y, Shen W.H.*, Cline HT
PubMed DOI
CSHP
8
Environ Pollut
Xenopus in revealing developmental toxicity and modeling human diseases
Gao J, Shen W.H.*
PubMed DOI
Environ Pollut
20202 papers
9
Neuroscientist
Wnt/β-Catenin Signaling in Neural Stem Cell Homeostasis and Neurological Diseases
Gao J, Liao Y, Qiu M, Shen W.H.*
PubMed DOI
Neuroscientist
10
Toxicology
d-Glucuronolactone attenuates para-xylene-induced defects in neuronal development and plasticity in Xenopus tectum in vivo
Liao Y, Luo Y, Ding N, Gao J, Wang X, Shen W.H.*
PubMed DOI
Toxicology
20182 papers
11
Nat Commun ★ Key Paper
Cell-autonomous regulation of structural and functional plasticity in inhibitory neurons by excitatory synaptic inputs
He H.Y., Shen W.H.*, Zheng L., Guo X., Cline H.T.*
PubMed DOI
Nat Commun
12
eLife
Role of the visual experience-dependent nascent proteome in neuronal plasticity
Liu H.H., McClatchy D.B., Schiapparelli L., Shen W.H., Yates J.R. 3rd, Cline H.T.*
PubMed DOI
eLife
2016–20175 papers
13
Dev Neurobiol
Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo
Ruan H, Gao J, Qi X, Tao Y, Guo X et al. Shen W.H.*
PubMed DOI
Dev Neurobiol
14
Neuron ★ Key Paper
Experience-Dependent Bimodal Plasticity of Inhibitory Neurons in Early Development
He H.Y., Shen W.H., Hiramoto M., Cline H.T.*
PubMed DOI
Neuron
15
Front Cell Neurosci
HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum
Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W.H.*
PubMed DOI
Front Cell Neurosci
16
Neuroscience
Increased apoptosis and abnormal visual behavior by histone modifications with exposure to para-xylene in developing Xenopus
Gao J, Ruan H, Qi X, Guo X et al. Shen W.H.*
PubMed DOI
Neuroscience
17
Front Cell Neurosci
Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum
Guo X, Ruan H, Li X et al. Shen W.H.*
PubMed DOI
Front Cell Neurosci
2006–2015Selected papers
18
PLoS ONE
HDAC1 Regulates the Proliferation of Radial Glial Cells in the Developing Xenopus Tectum
Tao Y, Ruan H, Guo X, Li L*, Shen W.H.* (2015)
PubMed DOI
PLoS ONE
19
Cell Rep ★ Featured
Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus
Shen W.H.#, Liu H.H., Schiapparelli L., McClatchy D., He H.Y., Yates J.R. 3rd, Cline H.T.* (2014)
PubMed DOI
Cell Rep
20
J Neurophysiol
Inhibition to excitation ratio regulates visual system responses and behavior in vivo
Shen W.H.#, McKeown C., Demas J., Cline H.T.* (2011)
PubMed DOI
J Neurophysiol
21
J Neurosci
Type A GABA-receptor-dependent synaptic transmission sculpts dendritic arbor structure in Xenopus tadpoles in vivo
Shen W.H.#, Da Silva J.S.#, He H.Y., Cline H.T.* (2009)
PubMed DOI
J Neurosci
22
Nat Neurosci
Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons
Ji Y.Y., Lu Y., Yang F., Shen W.H. et al., Lu B. (2010)
PubMed DOI
Nat Neurosci
23
Neuron ★ Cover
Activity-induced rapid synaptic maturation mediated by presynaptic cdc42 signaling
Shen W.H.#, Wu B.*, Zhang Z.J., Dou Y., Rao Z.R., Chen Y.R., Duan S.M.* (2006)
PubMed DOI
Neuron
24
Science ★ Landmark
Long-term potentiation of neuron-glia synapses mediated by Ca²⁺-permeable AMPA receptors
Ge W.P.#, Yang X.J.# et al. Shen W.H., Duan S.M.* (2006)
PubMed DOI
Science
25
PNAS
Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine
Yang Y.L., Ge W.P., Chen Y.R. Shen W.H. et al. Duan S.M.* (2003)
PubMed DOI
PNAS
For the complete publication list, search Wanhua Shen on PubMed or Google Scholar. * = corresponding author; # = co-first author.